save and load stopped working

Save and load have been working fine (X box and switch controlers.) Now when I press the buttons (Select+ x or y) nothing happens, and there is no notice in the bottom lefthand side. I know some emulators don't support this, but I'm talking about emulators that were working yesterday. However the select and start buttons still work in the game, strange. If you can thanks for helping.

Have you disabled controller autoconfiguration ?
Or maybe you have steam working in parallel ?

Not knowingly, and no I'm not running steam, Thanks for the help though.

Now really scratching my head.
Still no joy with "save and load"although I can set the emulators to auto save.
I have a back up on a separate drive, and that "Save load" works. Same pc same controllers.
So I copied the .emulation folder from the good copy to the not working set up. But it still wont work. So the error has to be in another file. I don't want to just delete the original as it's a 2tb build. Thanks for reading this